|Other Accession||NM_000236, NP_000227|
|Reactivity||Human, Rabbit, Guinea Pig|
|Predicted||Human, Rabbit, Guinea Pig|
|Alias Symbol||HDLCQ12, HL, HTGL, LIPH|
|Other Names||Hepatic triacylglycerol lipase, HL, Hepatic lipase, 18.104.22.168, Lipase member C, LIPC, HTGL|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-LIPC antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||LIPC antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the hydrolysis of triglycerides and phospholipids present in circulating plasma lipoproteins, including chylomicrons, intermediate density lipoproteins (IDL), low density lipoproteins (LDL) of large size and high density lipoproteins (HDL), releasing free fatty acids (FFA) and smaller lipoprotein particles (PubMed:7592706, PubMed:8798474, PubMed:12032167, PubMed:26193433). Also exhibits lysophospholipase activity (By similarity). Can hydrolyze both neutral lipid and phospholipid substrates but shows a greater binding affinity for neutral lipid substrates than phospholipid substrates (By similarity). In native LDL, preferentially hydrolyzes the phosphatidylcholine species containing polyunsaturated fatty acids at sn-2 position (PubMed:26193433).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Stahnke G.,et al.Differentiation 35:45-52(1987).
Datta S.,et al.J. Biol. Chem. 263:1107-1110(1988).
Martin G.A.,et al.J. Biol. Chem. 263:10907-10914(1988).
Cai S.J.,et al.Biochemistry 28:8966-8971(1989).
Ameis D.,et al.J. Biol. Chem. 265:6552-6555(1990).
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