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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   LIPC antibody - C-terminal region   

LIPC antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - LIPC antibody - C-terminal region AI14963

    WB Suggested Anti-LIPC Antibody Titration: 1.0 μg/ml
    Positive Control: Fetal Liver
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P11150
Other Accession NM_000236, NP_000227
Reactivity Human, Rabbit, Guinea Pig
Predicted Human, Rabbit, Guinea Pig
Host Rabbit
Clonality Polyclonal
Calculated MW 55kDa
Additional Information
Gene ID 3990
Alias Symbol HDLCQ12, HL, HTGL, LIPH
Other Names Hepatic triacylglycerol lipase, HL, Hepatic lipase,, Lipase member C, LIPC, HTGL
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-LIPC antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsLIPC antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms HTGL
Function Catalyzes the hydrolysis of triglycerides and phospholipids present in circulating plasma lipoproteins, including chylomicrons, intermediate density lipoproteins (IDL), low density lipoproteins (LDL) of large size and high density lipoproteins (HDL), releasing free fatty acids (FFA) and smaller lipoprotein particles (PubMed:7592706, PubMed:8798474, PubMed:12032167, PubMed:26193433). Also exhibits lysophospholipase activity (By similarity). Can hydrolyze both neutral lipid and phospholipid substrates but shows a greater binding affinity for neutral lipid substrates than phospholipid substrates (By similarity). In native LDL, preferentially hydrolyzes the phosphatidylcholine species containing polyunsaturated fatty acids at sn-2 position (PubMed:26193433).
Cellular Location Secreted.
Research Areas
Citations (0)

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Stahnke G.,et al.Differentiation 35:45-52(1987).
Datta S.,et al.J. Biol. Chem. 263:1107-1110(1988).
Martin G.A.,et al.J. Biol. Chem. 263:10907-10914(1988).
Cai S.J.,et al.Biochemistry 28:8966-8971(1989).
Ameis D.,et al.J. Biol. Chem. 265:6552-6555(1990).

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$ 389.00
Cat# AI14963
Availability: 2-3 days
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