MSR1 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | P21757 |
Other Accession | NM_138715, NP_619729 |
Reactivity | Human, Pig, Horse, Bovine, Dog |
Predicted | Horse, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 50kDa |
Gene ID | 4481 |
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Alias Symbol | CD204, SCARA1, SR-A, phSR1, phSR2, SRA |
Other Names | Macrophage scavenger receptor types I and II, Macrophage acetylated LDL receptor I and II, Scavenger receptor class A member 1, CD204, MSR1, SCARA1 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-MSR1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | MSR1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MSR1 |
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Synonyms | SCARA1 |
Function | Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL) (PubMed:2251254). Isoform III does not internalize acetylated LDL (PubMed:9548586). |
Cellular Location | Membrane; Single-pass type II membrane protein. |
Tissue Location | Isoform I, isoform II and isoform III are expressed in monocyte-derived macrophages. Isoform I and isoform II are expressed in the liver, placenta and brain. |
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Provided below are standard protocols that you may find useful for product applications.
References
Matsumoto A.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:9133-9137(1990).
Gough P.J.,et al.J. Lipid Res. 39:531-543(1998).
Nusbaum C.,et al.Nature 439:331-335(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Emi M.,et al.J. Biol. Chem. 268:2120-2125(1993).
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