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GYPA antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P02724 |
| Other Accession | NM_002099, NP_002090 |
| Reactivity | Human |
| Predicted | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 14kDa |
| Gene ID | 2993 |
|---|---|
| Alias Symbol | CD235a, GPA, GPErik, GPSAT, GpMiIII, HGpMiIII, HGpMiV, HGpMiX, HGpMiXI, HGpSta(C), MN, MNS, PAS-2 |
| Other Names | Glycophorin-A, MN sialoglycoprotein, PAS-2, Sialoglycoprotein alpha, CD235a, GYPA, GPA |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-GYPA antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | GYPA antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GYPA (HGNC:4702) |
|---|---|
| Synonyms | GPA |
| Function | Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane (PubMed:35835865). Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein Note=Appears to be colocalized with SLC4A1 |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Siebert P.D.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:1665-1669(1986).
Tate C.G.,et al.Biochem. J. 254:743-750(1988).
Kudo S.,et al.Proc. Natl. Acad. Sci. U.S.A. 86:4619-4623(1989).
Jawad K.,et al.Nucleic Acids Res. 18:5829-5836(1990).
Kudo S.,et al.J. Biochem. 116:183-192(1994).
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