RAP2B antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB |
|---|---|
| Primary Accession | P61225 |
| Other Accession | NM_002886, NP_002877 |
| Reactivity | Human, Mouse, Rat, Rabbit, Yeast, Bovine, Guinea Pig, Dog |
| Predicted | Human, Mouse, Rat, Rabbit, Pig, Yeast, Bovine, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 20kDa |
| Gene ID | 5912 |
|---|---|
| Alias Symbol | MGC20484 |
| Other Names | Ras-related protein Rap-2b, RAP2B |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-RAP2B antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | RAP2B antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RAP2B |
|---|---|
| Function | Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. Involved in EGFR and CHRM3 signaling pathways through stimulation of PLCE1. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May regulate membrane vesiculation in red blood cells. |
| Cellular Location | Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Note=Associated with red blood cells- released vesicles |
| Tissue Location | Expressed in red blood cells (at protein level). |

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Provided below are standard protocols that you may find useful for product applications.
References
Farrell F.X.,et al.Nucleic Acids Res. 18:4281-4281(1990).
Ohmstede C.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:6527-6531(1990).
Puhl H.L. III,et al.Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
Farrell F.X.,et al.Biochem. J. 289:349-355(1993).
Evellin S.,et al.J. Biol. Chem. 277:16805-16813(2002).
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