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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   GPIHBP1 Antibody - C-terminal region   

GPIHBP1 Antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - GPIHBP1 Antibody - C-terminal region AI15106

    WB Suggested Anti-GPIHBP1 Antibody Titration: 1.0 μg/ml
    Positive Control: HepG2 Whole Cell
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q8IV16
Other Accession NM_178172, NP_835466
Reactivity Human
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 18kDa
Additional Information
Gene ID 338328
Alias Symbol GPI-HBP1
Other Names Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1, GPI-HBP1, GPI-anchored HDL-binding protein 1, High density lipoprotein-binding protein 1, GPIHBP1, HBP1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-GPIHBP1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsGPIHBP1 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GPIHBP1
Synonyms HBP1
Function Mediates the transport of lipoprotein lipase LPL from the basolateral to the apical surface of endothelial cells in capillaries (By similarity). Anchors LPL on the surface of endothelial cells in the lumen of blood capillaries (By similarity). Protects LPL against loss of activity, and against ANGPTL4-mediated unfolding (PubMed:27929370, PubMed:29899144). Thereby, plays an important role in lipolytic processing of chylomicrons by LPL, triglyceride metabolism and lipid homeostasis (PubMed:19304573, PubMed:21314738). Binds chylomicrons and phospholipid particles that contain APOA5 (PubMed:17997385, PubMed:19304573). Binds high-density lipoprotein (HDL) and plays a role in the uptake of lipids from HDL (By similarity).
Cellular Location Apical cell membrane {ECO:0000250|UniProtKB:Q9D1N2}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q9D1N2}. Basolateral cell membrane {ECO:0000250|UniProtKB:Q9D1N2}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q9D1N2}. Cell membrane; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q9D1N2}
Research Areas
Citations (0)

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References

Shan Y.X.,et al.Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Gin P.,et al.Biochim. Biophys. Acta 1771:1464-1468(2007).
Young S.G.,et al.J. Lipid Res. 52:1869-1884(2011).
Wang J.,et al.Lipids Health Dis. 6:23-23(2007).

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$ 389.00
Cat# AI15106
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