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GPIHBP1 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q8IV16 |
| Other Accession | NM_178172, NP_835466 |
| Reactivity | Human |
| Predicted | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 18kDa |
| Gene ID | 338328 |
|---|---|
| Alias Symbol | GPI-HBP1 |
| Other Names | Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1, GPI-HBP1, GPI-anchored HDL-binding protein 1, High density lipoprotein-binding protein 1, GPIHBP1, HBP1 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-GPIHBP1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | GPIHBP1 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GPIHBP1 (HGNC:24945) |
|---|---|
| Synonyms | HBP1 |
| Function | Mediates the transport of lipoprotein lipase LPL from the basolateral to the apical surface of endothelial cells in capillaries (By similarity). Anchors LPL on the surface of endothelial cells in the lumen of blood capillaries (By similarity). Protects LPL against loss of activity, and against ANGPTL4-mediated unfolding (PubMed:27929370, PubMed:29899144). Thereby, plays an important role in lipolytic processing of chylomicrons by LPL, triglyceride metabolism and lipid homeostasis (PubMed:19304573, PubMed:21314738). Binds chylomicrons and phospholipid particles that contain APOA5 (PubMed:17997385, PubMed:19304573). Binds high-density lipoprotein (HDL) and plays a role in the uptake of lipids from HDL (By similarity). |
| Cellular Location | Apical cell membrane {ECO:0000250|UniProtKB:Q9D1N2}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q9D1N2}. Basolateral cell membrane {ECO:0000250|UniProtKB:Q9D1N2}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q9D1N2}. Cell membrane; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q9D1N2} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Shan Y.X.,et al.Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Gin P.,et al.Biochim. Biophys. Acta 1771:1464-1468(2007).
Young S.G.,et al.J. Lipid Res. 52:1869-1884(2011).
Wang J.,et al.Lipids Health Dis. 6:23-23(2007).
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