|Other Accession||NM_021147, NP_066970|
|Reactivity||Human, Mouse, Rabbit, Pig, Horse|
|Predicted||Human, Mouse, Rabbit, Pig, Horse|
|Alias Symbol||CCNU, FLJ22422, UDG2, UNG2|
|Other Names||Cyclin-O, CCNO|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-CCNO antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||CCNO antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Specifically required for generation of multiciliated cells, possibly by promoting a cell cycle state compatible with centriole amplification and maturation. Acts downstream of MCIDAS to promote mother centriole amplification and maturation in preparation for apical docking.|
|Cellular Location||Cytoplasm. Nucleus, nucleolus Note=Localizes to the apical part of cytoplasm|
|Tissue Location||Present in respiratory cells (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
Muller S.J.,et al.Biochim. Biophys. Acta 1088:197-207(1991).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Schmutz J.,et al.Nature 431:268-274(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Muller S.J.,et al.J. Biol. Chem. 268:1310-1319(1993).
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