TXNRD3 Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q86VQ6 |
Other Accession | NM_052883, NP_443115 |
Reactivity | Human, Mouse, Rabbit |
Predicted | Human, Mouse, Rabbit |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 70kDa |
Gene ID | 114112 |
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Alias Symbol | TGR, TR2, TRXR3 |
Other Names | Thioredoxin reductase 3, 1.8.1.9, Thioredoxin and glutathione reductase, Thioredoxin reductase TR2, TXNRD3 {ECO:0000312|EMBL:AAH50032.1} |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-TXNRD3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | TXNRD3 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TXNRD3 {ECO:0000312|EMBL:AAH50032.1} |
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Function | Displays thioredoxin reductase, glutaredoxin and glutathione reductase activities. Catalyzes disulfide bond isomerization. Promotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components (By similarity). |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q99MD6}. Nucleus {ECO:0000250|UniProtKB:Q99MD6}. Microsome {ECO:0000250|UniProtKB:Q99MD6}. Endoplasmic reticulum Note=Detected in cytoplasm and nucleus in late spermatids {ECO:0000250|UniProtKB:Q99MD6} |
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Provided below are standard protocols that you may find useful for product applications.
References
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Sun Q.-A.,et al.J. Biol. Chem. 274:24522-24530(1999).
Miranda-Vizuete A.,et al.Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Gerashchenko M.V.,et al.J. Biol. Chem. 285:4595-4602(2010).
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