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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   OST4 Antibody - C-terminal region   

OST4 Antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - OST4 Antibody - C-terminal region AI15258

    WB Suggested Anti-OST4 Antibody Titration: 1.0 μg/ml
    Positive Control: MCF7 Whole Cell
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P0C6T2
Other Accession NM_001134693, NP_001128165
Reactivity Human, Mouse, Rat, Dog
Predicted Human, Mouse, Rat, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 4kDa
Additional Information
Gene ID 100128731
Alias Symbol DKFZp586A0722
Other Names Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4, OST4
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-OST4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsOST4 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name OST4
Function Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. Specifically involved in maintaining stability of STT3A-containing OST complexes.
Cellular Location Endoplasmic reticulum. Endoplasmic reticulum membrane; Single- pass type III membrane protein. Note=The single transmembrane helix has a kink in the middle of the transmembrane span
Research Areas
Citations (0)

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References

Hillier L.W.,et al.Nature 434:724-731(2005).
Gayen S.,et al.Biochem. Biophys. Res. Commun. 409:572-576(2011).

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$ 389.00
Cat# AI15258
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