MAST1 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q9Y2H9 |
Other Accession | NM_014975, NP_055790 |
Reactivity | Human, Pig, Bovine, Dog |
Predicted | Human, Pig, Bovine, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 171kDa |
Gene ID | 22983 |
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Alias Symbol | KIAA0973, SAST, SAST170 |
Other Names | Microtubule-associated serine/threonine-protein kinase 1, 2.7.11.1, Syntrophin-associated serine/threonine-protein kinase, MAST1 (HGNC:19034) |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-MAST1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | MAST1 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MAST1 (HGNC:19034) |
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Function | Microtubule-associated protein essential for correct brain development (PubMed:30449657). Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins (By similarity). |
Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q9R1L5}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9R1L5}; Cytoplasmic side {ECO:0000250|UniProtKB:Q9R1L5}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9R1L5}. Cell projection, axon {ECO:0000250|UniProtKB:Q9R1L5}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q9R1L5}. Note=Also localized in the soma of neurons. Observed as punctate clusters in the processes of interneurons and along the cell body periphery. Colocalizes with syntrophins at the cell membrane. {ECO:0000250|UniProtKB:Q9R1L5} |
Tissue Location | Expressed in fetal brain. |
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Provided below are standard protocols that you may find useful for product applications.
References
Nagase T.,et al.DNA Res. 6:63-70(1999).
Grimwood J.,et al.Nature 428:529-535(2004).
Greenman C.,et al.Nature 446:153-158(2007).
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