RAB41 Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
 
| Application  
 | WB | 
|---|---|
| Primary Accession | Q5JT25 | 
| Other Accession | NM_001032726, NP_001027898 | 
| Reactivity | Human | 
| Predicted | Human | 
| Host | Rabbit | 
| Clonality | Polyclonal | 
| Calculated MW | 24kDa | 
| Gene ID | 347517 | 
|---|---|
| Other Names | Ras-related protein Rab-41, RAB41 | 
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. | 
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-RAB41 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. | 
| Precautions | RAB41 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. | 
| Name | RAB41 (HGNC:18293) | 
|---|---|
| Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (PubMed:23936529). RAB41 is required for normal Golgi ribbon organization and ER-to-Golgi trafficking (PubMed:23936529). | 
| Cellular Location | Cytoplasm. Note=punctate localization concentrated in ruffled regions at the cell periphery | 
| Tissue Location | Widely expressed in brain, testis, lung, heart, ovary, colon, kidney, uterus and spleen but not in liver | 

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Provided below are standard protocols that you may find useful for product applications.
References
Ross M.T.,et al.Nature 434:325-337(2005).
Guo J.H.,et al.DNA Seq. 14:431-435(2003).
Liu S.,et al.PLoS ONE 8:E71886-E71886(2013).

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