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C9orf24 Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q8NCR6 |
| Other Accession | NM_032596, NP_115985 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 29kDa |
| Gene ID | 84688 |
|---|---|
| Alias Symbol | CBE1, MGC32921, MGC33614, NYD-SP22, bA573M23.4 |
| Other Names | Spermatid-specific manchette-related protein 1, Ciliated bronchial epithelial protein 1, Testis development protein NYD-SP22, SMRP1, C9orf24, CBE1 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-C9orf24 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | C9orf24 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SPMIP6 (HGNC:19919) |
|---|---|
| Function | May participate in intramanchette transport and midpiece formation of the sperm tail. May play a potential role in somatic cell proliferation. |
| Cellular Location | Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q2MH31}. Nucleus Cytoplasm. Mitochondrion {ECO:0000250|UniProtKB:Q2MH31}. Cytoplasm, cytoskeleton, flagellum axoneme. Note=During spermatid elongation (step 10), localizes along the length of the manchette and later during the elongation process only at the distal ends of spermatid manchette (step 12). In late elongated spermatids (step 16), in the final steps of spermiogenesis, localization is restricted to the midpiece of the flagellum. Localizes at the contractile ring in dividing cells (By similarity). Predominantly perinuclear in bronchial epithelial cells but also detected in the nucleus in some primary epithelial cells and in a number of cell lines (PubMed:15242845) {ECO:0000250|UniProtKB:Q2MH31, ECO:0000269|PubMed:15242845} |
| Tissue Location | Expressed in testis (PubMed:28601408). Strongly expressed in ciliated epithelial cells with lower levels in goblet cells (at protein level) (PubMed:15242845) |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Yoshisue H.,et al.Am. J. Respir. Cell Mol. Biol. 31:491-500(2004).
Sha J.H.,et al.Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Humphray S.J.,et al.Nature 429:369-374(2004).
Haitchi H.M.,et al.Eur. Respir. J. 33:1095-1104(2009).
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