|Other Accession||NM_032596, NP_115985|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||CBE1, MGC32921, MGC33614, NYD-SP22, bA573M23.4|
|Other Names||Spermatid-specific manchette-related protein 1, Ciliated bronchial epithelial protein 1, Testis development protein NYD-SP22, SMRP1, C9orf24, CBE1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-C9orf24 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||C9orf24 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in spermatogenesis (By similarity). May be involved in differentiation or function of ciliated cells.|
|Cellular Location||Cytoplasm, cytoskeleton. Nucleus. Cytoplasm Note=Localizes to the manchette in elongating spermatids (By similarity). Predominantly perinuclear in bronchial epithelial cells but also detected in the nucleus in some primary epithelial cells and in a number of cell lines.|
|Tissue Location||Expressed in epithelial cells of nasal polyps and in intact epithelium of bronchial biopsies from subjects with and without asthma. Strong expression in columnar cells with little or no expression in basal epithelial cells along the basement membrane Strongly expressed in ciliated epithelial cells with lower levels in goblet cells (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
Yoshisue H.,et al.Am. J. Respir. Cell Mol. Biol. 31:491-500(2004).
Sha J.H.,et al.Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Humphray S.J.,et al.Nature 429:369-374(2004).
Haitchi H.M.,et al.Eur. Respir. J. 33:1095-1104(2009).
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