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> home > Products > Primary Antibodies > Developmental Biology > SERF1A Antibody - N-terminal region
SERF1A Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
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- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | O75920 |
| Other Accession | NM_022968, NP_075257 |
| Reactivity | Human, Mouse, Rat, Rabbit, Bovine, Guinea Pig |
| Predicted | Human, Mouse, Rat, Rabbit, Pig, Bovine, Guinea Pig |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 6kDa |
| Gene ID | 728492;8293 |
|---|---|
| Alias Symbol | 4F5, FAM2A, H4F5, SERF1, SERF1B, SMAM1 |
| Other Names | Small EDRK-rich factor 1, Protein 4F5, h4F5, SMA modifier 1, SERF1A, FAM2A, SERF1, SMAM1 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-SERF1A antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | SERF1A Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SERF1A |
|---|---|
| Synonyms | FAM2A, SERF1, SMAM1 |
| Function | Positive regulator of amyloid protein aggregation and proteotoxicity (PubMed:20723760, PubMed:22854022, PubMed:31034892). Induces conformational changes in amyloid proteins, such as APP, HTT, and SNCA, driving them into compact formations preceding the formation of aggregates (PubMed:20723760, PubMed:22854022, PubMed:31034892). |
| Cellular Location | Cytoplasm, cytosol. Nucleus |
| Tissue Location | Isoform Long is predominantly expressed in heart, brain and skeletal muscle. Isoform Short and Isoform Long are expressed throughout the central nervous system, including spinal cord |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Scharf J.M.,et al.Nat. Genet. 20:83-86(1998).
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$ 389.00
Cat# AI15460
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