|Other Accession||NM_024091, NP_076996|
|Reactivity||Human, Horse, Bovine|
|Predicted||Human, Horse, Bovine|
|Other Names||FAST kinase domain-containing protein 3, FASTKD3|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-FASTKD3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||FASTKD3 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for normal mitochondrial respiration (PubMed:20869947). Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND2, MT-ND3, MT-CYTB, MT-CO2, and MT-ATP8/6. Promotes MT-CO1 mRNA translation and increases mitochondrial complex IV assembly and activity (PubMed:27789713).|
|Tissue Location||Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in liver and thyroid|
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Schmutz J.,et al.Nature 431:268-274(2004).
Sjoeblom T.,et al.Science 314:268-274(2006).
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