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KDELR2 Antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - KDELR2 Antibody - middle region AI15507

    Host: Rabbit
    Target Name: KDELR2
    Sample Tissue: RPMI-8226 Whole cell lysate
    s
    Antibody Dilution: 1.0μg/ml
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P33947
Other Accession NM_001100603, NP_001094073
Reactivity Human
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 21kDa
Additional Information
Gene ID 11014
Alias Symbol ELP-1, ERD2.2
Other Names ER lumen protein-retaining receptor 2, ERD2-like protein 1, ELP-1, KDEL endoplasmic reticulum protein retention receptor 2, KDEL receptor 2, KDELR2, ERD2.2
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-KDELR2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsKDELR2 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KDELR2
Synonyms ERD2.2 {ECO:0000303|PubMed:1325562}
Function Receptor for the C-terminal sequence motif K-D-E-L that is present on endoplasmic reticulum resident proteins and that mediates their recycling from the Golgi back to the endoplasmic reticulum (PubMed:1325562, PubMed:18086916). Binding is pH dependent, and is optimal at pH 5-5.4 (By similarity).
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q5ZKX9}. Golgi apparatus membrane; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q5ZKX9}. Cytoplasmic vesicle, COPI-coated vesicle membrane; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q5ZKX9} Note=Localized in the Golgi in the absence of bound proteins with the sequence motif K-D-E-L. Trafficks back to the endoplasmic reticulum together with cargo proteins containing the sequence motif K-D-E-L
Research Areas
Citations (0)

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References

Lewis M.J.,et al.J. Mol. Biol. 226:913-916(1992).
Hsu V.W.,et al.Cell 69:625-635(1992).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 424:157-164(2003).
Scherer S.W.,et al.Science 300:767-772(2003).

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$ 389.00
Cat# AI15507
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