LACE1 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q8WV93 |
Other Accession | NM_145315, NP_660358 |
Reactivity | Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 53kDa |
Gene ID | 246269 |
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Alias Symbol | AFG1 |
Other Names | Lactation elevated protein 1, Protein AFG1 homolog, LACE1, AFG1 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-LACE1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | LACE1 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | AFG1L (HGNC:16411) |
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Function | Putative mitochondrial ATPase. Plays a role in mitochondrial morphology and mitochondrial protein metabolism. Promotes degradation of excess nuclear-encoded complex IV subunits (COX4I1, COX5A and COX6A1) and normal activity of complexes III and IV of the respiratory chain (PubMed:26759378, PubMed:27323408). Mediates mitochondrial translocation of TP53 and its transcription-independent apoptosis in response to genotoxic stress (PubMed:27323408). |
Cellular Location | Mitochondrion membrane |
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Provided below are standard protocols that you may find useful for product applications.
References
Abrahams B.S.,et al.Genomics 80:45-53(2002).
Mungall A.J.,et al.Nature 425:805-811(2003).
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