PDZD7 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q9H5P4 |
Other Accession | NM_024895, NP_079171 |
Reactivity | Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 57kDa |
Gene ID | 79955 |
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Alias Symbol | PDZK7 |
Other Names | PDZ domain-containing protein 7, PDZD7, PDZK7 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-PDZD7 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | PDZD7 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PDZD7 (HGNC:26257) |
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Function | In cochlear developing hair cells, essential in organizing the USH2 complex at stereocilia ankle links. Blocks inhibition of adenylate cyclase activity mediated by ADGRV1. |
Cellular Location | Cell projection, cilium. Nucleus Cell projection, stereocilium {ECO:0000250|UniProtKB:E9Q9W7} Note=Localizes at the ankle region of the stereocilia {ECO:0000250|UniProtKB:E9Q9W7} |
Tissue Location | Weakly expressed in the inner ear. Expressed in the retinal pigment epithelium. |
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Provided below are standard protocols that you may find useful for product applications.
References
Ebermann I.,et al.J. Clin. Invest. 120:1812-1823(2010).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 429:375-381(2004).
Schneider E.,et al.Hum. Mol. Genet. 18:655-666(2009).
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).
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