PSMG2 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application
| WB |
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Primary Accession | Q969U7 |
Other Accession | NM_020232, NP_064617 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Goat, Sheep, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Goat, Sheep, Horse, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 29kDa |
Gene ID | 56984 |
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Alias Symbol | CLAST3, HCCA3, HsT1707, MDS003, PAC2, TNFSF5IP1 |
Other Names | Proteasome assembly chaperone 2, PAC-2, Hepatocellular carcinoma-susceptibility protein 3, Tumor necrosis factor superfamily member 5-induced protein 1, PSMG2 {ECO:0000312|EMBL:AAH13356.1} |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-PSMG2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | PSMG2 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PSMG2 {ECO:0000312|EMBL:AAH13356.1} |
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Function | Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization. |
Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q9EST4}. |
Tissue Location | Widely expressed with highest levels in lung, brain and colon. Moderately expressed in muscle, stomach, spleen and heart Weakly expressed in small intestine, pancreas and liver. Highly expressed in hepatocellular carcinomas with low levels in surrounding liver tissue. |
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Provided below are standard protocols that you may find useful for product applications.
References
Gu J.,et al.Hematol. J. 1:206-217(2000).
Wang Z.-X.,et al.World J. Gastroenterol. 7:821-825(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Nusbaum C.,et al.Nature 437:551-555(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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