DTX4 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q9Y2E6 |
Other Accession | NM_015177, NP_055992 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 67kDa |
Gene ID | 23220 |
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Alias Symbol | RNF155 |
Other Names | E3 ubiquitin-protein ligase DTX4, 6.3.2.-, Protein deltex-4, Deltex4, RING finger protein 155, DTX4, KIAA0937, RNF155 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-DTX4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | DTX4 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DTX4 |
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Synonyms | KIAA0937, RNF155 |
Function | Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations (By similarity). Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4. |
Cellular Location | Cytoplasm. |
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Provided below are standard protocols that you may find useful for product applications.
References
Nagase T.,et al.DNA Res. 6:63-70(1999).
Storck S.,et al.Mol. Cell. Biol. 25:1437-1445(2005).
Cui J.,et al.Nat. Immunol. 13:387-395(2012).
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