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Tbc1d17 Antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q8BYH7 |
| Other Accession | NM_001042655, NP_001036120 |
| Reactivity | Human, Mouse, Rat, Goat, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Human, Mouse, Rat, Pig, Goat, Horse, Bovine, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 72kDa |
| Gene ID | 233204 |
|---|---|
| Alias Symbol | BC017607 |
| Other Names | TBC1 domain family member 17, Tbc1d17 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Tbc1d17 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Tbc1d17 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Tbc1d17 |
|---|---|
| Function | Probable GTPase-activating protein that inhibits RAB8A/B function. Reduces Rab8 recruitment to tubules emanating from the endocytic recycling compartment (ERC) and inhibits Rab8-mediated endocytic trafficking, such as that of transferrin receptor (TfR). Involved in regulation of autophagy. |
| Cellular Location | Cytoplasmic vesicle, autophagosome {ECO:0000250|UniProtKB:Q9HA65}. Cytoplasm {ECO:0000250|UniProtKB:Q9HA65}. Recycling endosome {ECO:0000250|UniProtKB:Q9HA65}. Note=In the presence of optineurin/OPTN, may be recruited to recycling endosomes {ECO:0000250|UniProtKB:Q9HA65} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Carninci P.,et al.Science 309:1559-1563(2005).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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