Tbc1d17 Antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q8BYH7 |
Other Accession | NM_001042655, NP_001036120 |
Reactivity | Human, Mouse, Rat, Goat, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Pig, Goat, Horse, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 72kDa |
Gene ID | 233204 |
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Alias Symbol | BC017607 |
Other Names | TBC1 domain family member 17, Tbc1d17 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Tbc1d17 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Tbc1d17 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Tbc1d17 |
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Function | Probable GTPase-activating protein that inhibits RAB8A/B function. Reduces Rab8 recruitment to tubules emanating from the endocytic recycling compartment (ERC) and inhibits Rab8-mediated endocytic trafficking, such as that of transferrin receptor (TfR). Involved in regulation of autophagy. |
Cellular Location | Cytoplasmic vesicle, autophagosome {ECO:0000250|UniProtKB:Q9HA65}. Cytoplasm {ECO:0000250|UniProtKB:Q9HA65}. Recycling endosome {ECO:0000250|UniProtKB:Q9HA65}. Note=In the presence of optineurin/OPTN, may be recruited to recycling endosomes {ECO:0000250|UniProtKB:Q9HA65} |
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Provided below are standard protocols that you may find useful for product applications.
References
Carninci P.,et al.Science 309:1559-1563(2005).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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