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REV1 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q9UBZ9 |
| Other Accession | XP_005264024 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 137kDa |
| Gene ID | 51455 |
|---|---|
| Alias Symbol | REV1, REV1L, |
| Other Names | DNA repair protein REV1, 2.7.7.-, Alpha integrin-binding protein 80, AIBP80, Rev1-like terminal deoxycytidyl transferase, REV1, REV1L |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 &mu, l of distilled water. Final Anti-REV1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | REV1 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | REV1 |
|---|---|
| Synonyms | REV1L |
| Function | Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents. |
| Cellular Location | Nucleus. |
| Tissue Location | Ubiquitous. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
References
Lin W.,et al.Nucleic Acids Res. 27:4468-4475(1999).
Gibbs P.E.M.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:4186-4191(2000).
Masuda Y.,et al.J. Biol. Chem. 276:15051-15058(2001).
Murakumo Y.,et al.J. Biol. Chem. 276:35644-35651(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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