SMU1 Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB |
|---|---|
| Primary Accession | Q2TAY7 |
| Other Accession | NP_060695 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 56kDa |
| Gene ID | 55234 |
|---|---|
| Alias Symbol | SMU1, |
| Other Names | WD40 repeat-containing protein SMU1, Smu-1 suppressor of mec-8 and unc-52 protein homolog, WD40 repeat-containing protein SMU1, N-terminally processed, SMU1 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 &mu, l of distilled water. Final Anti-SMU1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | SMU1 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SMU1 |
|---|---|
| Function | Involved in pre-mRNA splicing as a component of the spliceosome (PubMed:28781166). Regulates alternative splicing of the HSPG2 pre-mRNA (By similarity). Required for normal accumulation of IK (PubMed:24945353). Required for normal mitotic spindle assembly and normal progress through mitosis (By similarity). |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q99M63}. Nucleus. Nucleus speckle {ECO:0000250|UniProtKB:Q76B40}. Note=Colocalizes with SRSF1 in nuclear speckles. {ECO:0000250|UniProtKB:Q76B40} |

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Provided below are standard protocols that you may find useful for product applications.
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Humphray S.J.,et al.Nature 429:369-374(2004).
Bienvenut W.V.,et al.Submitted (DEC-2008) to UniProtKB.
Gauci S.,et al.Anal. Chem. 81:4493-4501(2009).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
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