DRD1 / Dopamine Receptor D1 Antibody (Extracellular Domain)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | P21728 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 49kDa |
Dilution | IHC-P (10 µg/ml) |
Gene ID | 1812 |
---|---|
Other Names | D(1A) dopamine receptor, Dopamine D1 receptor, DRD1 |
Target/Specificity | Human DRD1. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
Precautions | DRD1 / Dopamine Receptor D1 Antibody (Extracellular Domain) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DRD1 |
---|---|
Function | Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase. |
Cellular Location | Cell membrane {ECO:0000250|UniProtKB:P18901}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P18901}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P18901}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P18901}. Cell projection, cilium membrane; Multi-pass membrane protein. Cell projection, dendrite {ECO:0000250|UniProtKB:Q61616}. Cell projection, dendritic spine {ECO:0000250|UniProtKB:Q61616}. Note=Transport from the endoplasmic reticulum to the cell surface is regulated by interaction with DNAJC14 {ECO:0000250|UniProtKB:P18901} |
Tissue Location | Detected in caudate, nucleus accumbens and in the olfactory tubercle. |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
References
Dearry A.,et al.Nature 347:72-76(1990).
Zhou Q.-Y.,et al.Nature 347:76-80(1990).
Sunahara R.K.,et al.Nature 347:80-83(1990).
Ohara K.,et al.Neuropsychopharmacology 8:131-135(1993).
Suwa M.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
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