|Dilution||IHC-P (2-4 µg/ml)|
|Other Names||G-protein coupled receptor 39, GPR39|
|Target/Specificity||Human GPR39. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except CEP250 (65%).|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||GPR39 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Zn(2+) acts as an agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in many tissues, including the stomach, intestine and hypothalamus.|
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Provided below are standard protocols that you may find useful for product applications.
Zn(2+) acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity).
McKee K.K.,et al.Genomics 46:426-434(1997).
Kaighin V.A.,et al.Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Storjohann L.,et al.Biochemistry 47:9198-9207(2008).
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