GPR6 Antibody (Cytoplasmic Domain)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | P46095 |
Reactivity | Human, Mouse, Rabbit, Hamster, Monkey, Pig, Bovine, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 38kDa |
Dilution | IHC-P (6-9 µg/ml) |
Gene ID | 2830 |
---|---|
Other Names | G-protein coupled receptor 6, Sphingosine 1-phosphate receptor GPR6, GPR6 |
Target/Specificity | Human GPR6. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GPR12 (60%). |
Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
Precautions | GPR6 Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GPR6 |
---|---|
Function | Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity). |
Cellular Location | Cell membrane; Multi-pass membrane protein Note=Detected in the intracellular compartments. It is currently unclear whether this is a cell surface or intracellular receptor |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity).
References
Heiber M.,et al.DNA Cell Biol. 14:25-35(1995).
Song Z.-H.,et al.Genomics 28:347-349(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mungall A.J.,et al.Nature 425:805-811(2003).
Uhlenbrock K.,et al.Cell. Signal. 14:941-953(2002).
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