|Dilution||IHC-P (2.8-4.6 µg/ml)|
|Other Names||Proteinase-activated receptor 3, PAR-3, Coagulation factor II receptor-like 2, Thrombin receptor-like 2, F2RL2, PAR3|
|Target/Specificity||Human F2RL2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except F2R (42%), F2RL1 (37%).|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||F2RL2 / PAR3 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.
Ishihara H.,et al.Nature 386:502-506(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Schmutz J.,et al.Nature 431:268-274(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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