|Dilution||IHC-P (1-3 µg/ml)|
|Other Names||Growth hormone secretagogue receptor type 1, GHS-R, GH-releasing peptide receptor, GHRP, Ghrelin receptor, GHSR|
|Target/Specificity||Human Ghrelin Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||GHSR / Ghrelin Receptor Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK- 0677, adenosine).|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Pituitary and hypothalamus.|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine).
Howard A.D.,et al.Science 273:974-977(1996).
Petersenn S.,et al.Endocrinology 142:2649-2659(2001).
Kopatz S.A.,et al.Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Smith R.G.,et al.Endocrine 14:9-14(2001).
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