Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
PDE6A Antibody (N-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | P16499 |
| Reactivity | Human, Mouse, Hamster, Monkey |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 100kDa |
| Dilution | IHC-P (10-15 µg/ml) |
| Gene ID | 5145 |
|---|---|
| Other Names | Rod cGMP-specific 3', 5'-cyclic phosphodiesterase subunit alpha, GMP-PDE alpha, 3.1.4.35, PDE V-B1, PDE6A, PDEA |
| Target/Specificity | Human PDE6A / PDE6 Alpha. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
| Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
| Precautions | PDE6A Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PDE6A (HGNC:8785) |
|---|---|
| Synonyms | PDEA |
| Function | Rod-specific cGMP phosphodiesterase that catalyzes the hydrolysis of 3',5'-cyclic GMP (PubMed:20940301). This protein participates in processes of transmission and amplification of the visual signal. |
| Cellular Location | Cell membrane; Lipid-anchor; Cytoplasmic side. Cell projection, cilium, photoreceptor outer segment |
| Volume | 238 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
This protein participates in processes of transmission and amplification of the visual signal.
References
Pittler S.J.,et al.Genomics 6:272-283(1990).
Pittler S.J.,et al.Submitted (MAY-1995) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Huang S.H.,et al.Nat. Genet. 11:468-471(1995).
Dryja T.P.,et al.Invest. Ophthalmol. Vis. Sci. 40:1859-1865(1999).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Shipping Information
