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ADGRL3 / LPHN3 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | Q9HAR2 |
| Reactivity | Human, Mouse, Rabbit, Monkey, Chicken, Horse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 162kDa |
| Dilution | IHC-P (2 µg/ml) |
| Gene ID | 23284 |
|---|---|
| Other Names | Latrophilin-3, Calcium-independent alpha-latrotoxin receptor 3, CIRL-3, Lectomedin-3, LPHN3, KIAA0768, LEC3 |
| Target/Specificity | Human LPHN3. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
| Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
| Precautions | ADGRL3 / LPHN3 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ADGRL3 (HGNC:20974) |
|---|---|
| Function | Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells (PubMed:26235030). Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Cell projection, axon {ECO:0000250|UniProtKB:Q80TS3}. Cell junction {ECO:0000250|UniProtKB:Q80TS3} |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
May be involved in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex (By similarity).
References
Douangpanya J.,et al.Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Nagase T.,et al.DNA Res. 5:277-286(1998).
Domene S.,et al.Am. J. Med. Genet. B Neuropsychiatr. Genet. 156:11-18(2011).
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