PYGM Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| IHC-P |
|---|---|
| Primary Accession | P11217 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 97kDa |
| Dilution | IHC-P (20 µg/ml) |
| Gene ID | 5837 |
|---|---|
| Other Names | Glycogen phosphorylase, muscle form, 2.4.1.1, Myophosphorylase, PYGM |
| Target/Specificity | Human PYGM / Phosphorylase b. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except RARRES1 (57%). |
| Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
| Precautions | PYGM Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PYGM (HGNC:9726) |
|---|---|
| Function | Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis. |
| Volume | 50 µl |

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Provided below are standard protocols that you may find useful for product applications.
Background
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
References
Burke J.,et al.Proteins 2:177-187(1987).
Kubisch C.,et al.Hum. Mutat. 12:27-32(1998).
Carty M.D.,et al.Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Taylor T.D.,et al.Nature 440:497-500(2006).
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