ADGRE3 / EMR3 Antibody (N-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| IHC-P |
|---|---|
| Primary Accession | Q9BY15 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 73kDa |
| Dilution | IHC-P (10 µg/ml) |
| Gene ID | 84658 |
|---|---|
| Other Names | EGF-like module-containing mucin-like hormone receptor-like 3, EGF-like module receptor 3, EGF-like module-containing mucin-like hormone receptor-like 3 subunit alpha, EGF-like module-containing mucin-like hormone receptor-like 3 subunit beta, EMR3 |
| Target/Specificity | Human EMR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
| Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
| Precautions | ADGRE3 / EMR3 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ADGRE3 (HGNC:23647) |
|---|---|
| Synonyms | EMR3 |
| Function | Orphan receptor that may play a role myeloid-myeloid interactions during immune and inflammatory responses. A ligand for the soluble form of this receptor is present at the surface of monocytes- derived macrophages and activated neutrophils. |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Displays a predominantly leukocyte-restricted expression, with highest levels in neutrophils, monocytes and macrophages. |
| Volume | 50 µl |

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Provided below are standard protocols that you may find useful for product applications.
Background
Receptor probably involved in myeloid interactions during immune and inflammatory responses. A ligand for the soluble form of this receptor is present at the surface of momocytes- derived macrophages and activated neutrophils.
References
Stacey M.,et al.J. Biol. Chem. 276:18863-18870(2001).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Grimwood J.,et al.Nature 428:529-535(2004).
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