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RXFP3 Antibody (Cytoplasmic Domain)

Rabbit Polyclonal Antibody

     
  • IHC - RXFP3 Antibody (Cytoplasmic Domain) ALS10447
    Anti-RXFP3 antibody ALS10447 IHC of human brain, neurons and glia.
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession Q9NSD7
Reactivity Human, Hamster
Host Rabbit
Clonality Polyclonal
Calculated MW 51kDa
Dilution IHC-P (14-28 µg/ml)
Additional Information
Gene ID 51289
Other Names Relaxin-3 receptor 1, RLN3 receptor 1, G protein-coupled receptor SALPR, G-protein coupled receptor GPCR135, Relaxin family peptide receptor 3, Somatostatin- and angiotensin-like peptide receptor, RXFP3, RLN3R1, SALPR
Target/Specificity Human RXFP3. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except VGLL4 (45%).
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsRXFP3 Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RXFP3
Synonyms GPCR135, RLN3R1, SALPR
Function Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation.

References

Matsumoto M.,et al.Gene 248:183-189(2000).
Kopatz S.A.,et al.Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
Liu C.,et al.J. Biol. Chem. 278:50754-50764(2003).

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$ 467.50
Cat# ALS10447
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