|Dilution||IHC-P (10 µg/ml)|
|Other Names||Somatostatin receptor type 5, SS-5-R, SS5-R, SS5R, SSTR5|
|Target/Specificity||Human SSTR5. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||SSTR5 Antibody (Extracellular Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Increases cell growth inhibition activity of SSTR2 following heterodimerization.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Adult pituitary gland, heart, small intestine, adrenal gland, cerebellum and fetal hypothalamus. No expression in fetal or adult kidney, liver, pancreas, uterus, spleen, lung, thyroid or ovary.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Increases cell growth inhibition activity of SSTR2 following heterodimerization.
Panetta R.,et al.Mol. Pharmacol. 45:417-427(1994).
Yamada Y.,et al.Biochem. Biophys. Res. Commun. 195:844-852(1993).
O'Carroll A.-M.,et al.Mol. Pharmacol. 46:291-298(1994).
Petersenn S.,et al.Endocrinology 143:2626-2634(2002).
Daniels R.J.,et al.Hum. Mol. Genet. 10:339-352(2001).
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