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ADGRE5 / CD97 Antibody (N-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, ICC |
|---|---|
| Primary Accession | P48960 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 92kDa |
| Dilution | IHC-P (5 µg/ml) |
| Gene ID | 976 |
|---|---|
| Other Names | CD97 antigen, Leukocyte antigen CD97, CD97, CD97 antigen subunit alpha, CD97 antigen subunit beta, CD97 |
| Target/Specificity | Human CD97. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MAP3K12 (58%). |
| Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
| Precautions | ADGRE5 / CD97 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ADGRE5 (HGNC:1711) |
|---|---|
| Function | Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration. |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q9Z0M6}; Multi-pass membrane protein |
| Tissue Location | Broadly expressed, found on most hematopoietic cells, including activated lymphocytes, monocytes, macrophages, dendritic cells, and granulocytes. Expressed also abundantly by smooth muscle cells. Expressed in thyroid, colorectal, gastric, esophageal and pancreatic carcinomas too. Expression are increased under inflammatory conditions in the CNS of multiple sclerosis and in synovial tissue of patients with rheumatoid arthritis. Increased expression of CD97 in the synovium is accompanied by detectable levels of soluble CD97 in the synovial fluid |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration (By similarity).
References
Hamann J.,et al.J. Immunol. 155:1942-1950(1995).
Hamann J.,et al.Genomics 32:144-147(1996).
Hamann J.,et al.Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases.
Gray J.X.,et al.J. Immunol. 157:5438-5447(1996).
Suwa M.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
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