GPR26 Antibody (Cytoplasmic Domain)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | Q8NDV2 |
Reactivity | Human, Monkey, Pig, Horse, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 38kDa |
Dilution | IHC-P (6-15 µg/ml) |
Gene ID | 2849 |
---|---|
Other Names | G-protein coupled receptor 26, GPR26 |
Target/Specificity | Human GPR26. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
Precautions | GPR26 Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GPR26 |
---|---|
Function | Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Location | Highly expressed in the CNS, the highest expression is seen in the amygdala, hippocampus and thalamus. Weak expression is detected in testis. Down-regulated in glioblastoma |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP.
References
Jones G.,et al.Submitted (AUG-2002) to the EMBL/GenBank/DDBJ databases.
Boulay J.L.,et al.Submitted (AUG-2002) to the EMBL/GenBank/DDBJ databases.
Jones P.G.,et al.Biochim. Biophys. Acta 1770:890-901(2007).
Carter A.N.,et al.Mol. Cell. Probes 22:133-137(2008).
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