ADRB3 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | P13945 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 44kDa |
Dilution | IHC-P (20-40 µg/ml) |
Gene ID | 155 |
---|---|
Other Names | Beta-3 adrenergic receptor, Beta-3 adrenoreceptor, Beta-3 adrenoceptor, ADRB3, ADRB3R, B3AR |
Target/Specificity | Human ADRB3. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except OR2G3 (44%). |
Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
Precautions | ADRB3 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ADRB3 |
---|---|
Synonyms | ADRB3R, B3AR |
Function | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta- 3 is involved in the regulation of lipolysis and thermogenesis. |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Location | Expressed mainly in adipose tissues. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
References
Emorine L.J.,et al.Science 245:1118-1121(1989).
van Spronsen A.,et al.Eur. J. Biochem. 213:1117-1124(1993).
Lelias J.M.,et al.FEBS Lett. 324:127-130(1993).
Kopatz S.A.,et al.Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
Granneman J.G.,et al.Mol. Pharmacol. 42:964-970(1992).
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