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T1R3 / TAS1R3 Antibody (N-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | Q7RTX0 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 93kDa |
| Dilution | IHC-P (19 µg/ml) |
| Gene ID | 83756 |
|---|---|
| Other Names | Taste receptor type 1 member 3, Sweet taste receptor T1R3, TAS1R3, T1R3, TR3 |
| Target/Specificity | Human TAS1R3. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
| Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
| Precautions | T1R3 / TAS1R3 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TAS1R3 |
|---|---|
| Synonyms | T1R3, TR3 |
| Function | Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
| Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.
References
Suwa M.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
Li X.,et al.Proc. Natl. Acad. Sci. U.S.A. 99:4692-4696(2002).
Ariyasu T.,et al.In Vitro Cell. Dev. Biol. Anim. 39:80-88(2003).
Jiang P.,et al.J. Biol. Chem. 279:45068-45075(2004).
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