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P2RX3 / P2X3 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | P56373 |
| Reactivity | Human, Monkey |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 44kDa |
| Dilution | IHC-P (10 µg/ml) |
| Gene ID | 5024 |
|---|---|
| Other Names | P2X purinoceptor 3, P2X3, ATP receptor, Purinergic receptor, P2RX3 |
| Target/Specificity | Human P2RX3 / P2X3. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
| Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
| Precautions | P2RX3 / P2X3 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | P2RX3 |
|---|---|
| Function | Extracellular ATP-activated non-selective cation channel (PubMed:10440098, PubMed:27626375, PubMed:29674445, PubMed:31232692). Plays particularly important role in sensory neurons where its activation is critical for gustatory, nociceptive responses, visceral reflexes and sensory hypersensitization (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein Note=Localizes to neuronal cell body of sensory neurons {ECO:0000250|UniProtKB:P49654} |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Receptor for ATP that acts as a ligand-gated ion channel.
References
Garcia-Guzman M.,et al.Mol. Pharmacol. 51:109-118(1997).
Funatsuki K.,et al.Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases.
Taylor T.D.,et al.Nature 440:497-500(2006).
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