SRI / Sorcin Antibody (aa50-100)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | P30626 |
Reactivity | Human, Mouse, Rat, Monkey, Chicken, Opossum, Horse, Xenopus, Bovine, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 22kDa |
Dilution | IHC-P (10 µg/ml), WB (0.5-2 µg/ml), |
Gene ID | 6717 |
---|---|
Other Names | Sorcin, 22 kDa protein, CP-22, CP22, V19, SRI |
Target/Specificity | A portion of amino acids 50-100 of human Sorcin |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
Precautions | SRI / Sorcin Antibody (aa50-100) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SRI |
---|---|
Function | Calcium-binding protein that modulates excitation-contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Modulates the activity of RYR2 calcium channels. |
Cellular Location | Cytoplasm. Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=Relocates to the sarcoplasmic reticulum membrane in response to elevated calcium levels |
Tissue Location | Detected in cardiac myocytes. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Calcium-binding protein that modulates excitation- contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Modulates the activity of RYR2 calcium channels.
References
Wang S.L.,et al.Biochim. Biophys. Acta 1260:285-293(1995).
Lee W.P.,et al.Arch. Biochem. Biophys. 325:217-226(1996).
Sugimoto Y.,et al.Submitted (MAR-1990) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Oh J.H.,et al.Mamm. Genome 16:942-954(2005).
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