Glycophorin A+B Antibody (clone HIR2)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, FC |
---|---|
Primary Accession | P02724 |
Other Accession | P06028 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | HIR2 |
Calculated MW | 16331 Da |
Dilution | IHC-P (1:50) |
Gene ID | 2993 |
---|---|
Other Names | Glycophorin-A, MN sialoglycoprotein, PAS-2, Sialoglycoprotein alpha, CD235a, GYPA, GPA |
Reconstitution & Storage | Store undiluted at 4 degrees C |
Precautions | Glycophorin A+B Antibody (clone HIR2) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GYPA (HGNC:4702) |
---|---|
Synonyms | GPA |
Function | Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane (PubMed:35835865). Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. |
Cellular Location | Cell membrane; Single-pass type I membrane protein Note=Appears to be colocalized with SLC4A1 |
Volume | 50 µl |
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