ALS2CR1 / NIF3L1 Antibody (C-Terminus)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q9GZT8 |
Reactivity | Human, Monkey |
Host | Goat |
Clonality | Polyclonal |
Calculated MW | 42kDa |
Dilution | ELISA (1:32000), IHC-P (2.5 µg/ml), WB (0.2-1 µg/ml) |
Gene ID | 60491 |
---|---|
Other Names | Putative GTP cyclohydrolase 1 type 2 NIF3L1, 3.5.4.16, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein, GTP cyclohydrolase I, NIF3-like protein 1, NIF3L1, ALS2CR1 |
Target/Specificity | Human NIF3L1. This antibody is expected to recognise both reported isoforms. Variants (NP_001135827.1; NP_068596.2) encode the same isoform. |
Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
Precautions | ALS2CR1 / NIF3L1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | NIF3L1 (HGNC:13390) |
---|---|
Function | May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation. |
Cellular Location | Cytoplasm. Nucleus {ECO:0000250|UniProtKB:Q9EQ80} Note=Interaction with COPS2 may regulate localization to the nucleus {ECO:0000250|UniProtKB:Q9EQ80} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Converts GTP to dihydroneopterin triphosphate.
References
Tascou S.,et al.Cytogenet. Cell Genet. 90:330-336(2000).
Hadano S.,et al.Genomics 71:200-213(2001).
Merla G.,et al.Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
Mao Y.M.,et al.Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases.
Huang C.,et al.Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.
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