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ASS1 / ASS Antibody (Internal)

Goat Polyclonal Antibody

     
  • IHC - ASS1 / ASS Antibody (Internal) ALS13090
    Anti-ASS1 antibody IHC of human kidney.
    detail
  • IHC - ASS1 / ASS Antibody (Internal) ALS13090
    Anti-ASS1 antibody IHC of human liver.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E, IP
Primary Accession P00966
Reactivity Human, Mouse, Rat, Monkey, Pig, Horse, Bovine, Dog
Host Goat
Clonality Polyclonal
Calculated MW 47kDa
Dilution ELISA (1:64000), IHC-P (2.5 µg/ml), WB (0.01-0.03 µg/ml)
Additional Information
Gene ID 445
Other Names Argininosuccinate synthase, 6.3.4.5, Citrulline--aspartate ligase, ASS1, ASS
Target/Specificity Human ASS1. The variants represent identical protein (NP_000041.2 and NP_446464.1).
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsASS1 / ASS Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ASS1 (HGNC:758)
Function One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues.
Cellular Location Cytoplasm, cytosol
Tissue Location Expressed in adult liver.
Research Areas
Citations (0)
citation

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Background

Is indirectly involved in the control of blood pressure.

References

Bock H.-G.O.,et al.Nucleic Acids Res. 11:6505-6512(1983).
Freytag S.O.,et al.J. Biol. Chem. 259:3160-3166(1984).
Haeberle J.,et al.Hum. Genet. 110:327-333(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Jinno Y.,et al.J. Inherit. Metab. Dis. 8:157-159(1985).

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$ 467.50
Cat# ALS13090
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