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PXN / Paxillin Antibody (Tyr118)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | P49023 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Monkey, Chicken, Horse, Xenopus, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 65kDa |
| Dilution | IHC-P (10 µg/ml), WB (1:500-1:1000), |
| Gene ID | 5829 |
|---|---|
| Other Names | Paxillin, PXN |
| Target/Specificity | endogenous levels of total Paxillin protein |
| Reconstitution & Storage | Aliquot and store at -20°C. Minimize freezing and thawing. |
| Precautions | PXN / Paxillin Antibody (Tyr118) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PXN |
|---|---|
| Function | Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Recruits other proteins such as TRIM15 to focal adhesion. |
| Cellular Location | Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cytoplasm, cell cortex {ECO:0000250|UniProtKB:Q8VI36}. Note=Colocalizes with integrins at the cell periphery. Colocalize with PXN to membrane ruffles and the leading edge of migrating cells (PubMed:23128389). {ECO:0000250, ECO:0000269|PubMed:23128389} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
References
Salgia R.,et al.J. Biol. Chem. 270:5039-5047(1995).
Yamagata K.,et al.Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
Mazaki Y.,et al.J. Biol. Chem. 272:7437-7444(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
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