OCIAD1 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF, E |
---|---|
Primary Accession | Q9NX40 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 28kDa |
Dilution | IHC-P (5 µg/ml), WB (1-2 µg/ml), |
Gene ID | 54940 |
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Other Names | OCIA domain-containing protein 1, Ovarian carcinoma immunoreactive antigen, OCIAD1, OCIA |
Target/Specificity | Human OCIAD1 |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
Precautions | OCIAD1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | OCIAD1 (HGNC:16074) |
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Function | Maintains stem cell potency (By similarity). Increases STAT3 phosphorylation and controls ERK phosphorylation (By similarity). May act as a scaffold, increasing STAT3 recruitment onto endosomes (By similarity). Involved in integrin-mediated cancer cell adhesion and colony formation in ovarian cancer (PubMed:20515946). |
Cellular Location | Endosome {ECO:0000250|UniProtKB:Q9CRD0}. |
Tissue Location | Isoform 1 is highly expressed in many tissues, including testis, brain, placenta, ovary, prostate and mammary gland Isoform 2 expression is restricted to the central nervous system including brain, cerebellum and spinal cord |
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Provided below are standard protocols that you may find useful for product applications.
References
Luo L.Y.,et al.Biochem. Biophys. Res. Commun. 280:401-406(2001).
Xu X.,et al.Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
Li W.B.,et al.Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
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