CPS1 Antibody (clone 8H8)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P31327 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 8H8 |
Calculated MW | 165kDa |
Dilution | IHC-P (5 µg/ml) |
Gene ID | 1373 |
---|---|
Other Names | Carbamoyl-phosphate synthase [ammonia], mitochondrial, 6.3.4.16, Carbamoyl-phosphate synthetase I, CPSase I, CPS1 |
Target/Specificity | Human CPS1 |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
Precautions | CPS1 Antibody (clone 8H8) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CPS1 |
---|---|
Function | Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell. |
Cellular Location | Mitochondrion. Nucleus, nucleolus. Cell membrane {ECO:0000250|UniProtKB:Q8C196}; Peripheral membrane protein; Extracellular side {ECO:0000250|UniProtKB:Q8C196} Note=Localizes to the cell surface of hepatocytes {ECO:0000250|UniProtKB:Q8C196} |
Tissue Location | Primarily in the liver and small intestine. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell.
References
Haraguchi Y.,et al.Gene 107:335-340(1991).
Finckh U.,et al.Hum. Mutat. 12:206-211(1998).
Summar M.L.,et al.Gene 311:51-57(2003).
Huo R.,et al.Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
Funghini S.,et al.Hum. Mutat. 22:340-341(2003).
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