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DLX2 Antibody (clone 2B12)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q07687 |
| Reactivity | Human, Mouse |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 2B12 |
| Calculated MW | 34kDa |
| Dilution | IHC-P (5 µg/ml) |
| Gene ID | 1746 |
|---|---|
| Other Names | Homeobox protein DLX-2, DLX2 |
| Target/Specificity | Human Dlx2 |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
| Precautions | DLX2 Antibody (clone 2B12) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DLX2 |
|---|---|
| Function | Acts as a transcriptional activator (By similarity). Activates transcription of CGA/alpha-GSU, via binding to the downstream activin regulatory element (DARE) in the gene promoter (By similarity). Plays a role in terminal differentiation of interneurons, such as amacrine and bipolar cells in the developing retina. Likely to play a regulatory role in the development of the ventral forebrain (By similarity). May play a role in craniofacial patterning and morphogenesis (By similarity). |
| Cellular Location | Nucleus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis.
References
McGuinness T.,et al.Genomics 35:473-485(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Selski D.J.,et al.Gene 132:301-303(1993).
Simeone A.,et al.Proc. Natl. Acad. Sci. U.S.A. 91:2250-2254(1994).
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