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PCSK1 Antibody (clone 3D2)

Mouse Monoclonal Antibody

     
  • WB - PCSK1 Antibody (clone 3D2) ALS14054
    PCSK1 monoclonal antibody clone 3D2. Western blot of PCSK1 expression in PC-12.
    detail
  • WB - PCSK1 Antibody (clone 3D2) ALS14054
    PCSK1 monoclonal antibody clone 3D2. Western blot of PCSK1 expression in NIH/3T3.
    detail
  • IF - PCSK1 Antibody (clone 3D2) ALS14054
    Immunofluorescence of monoclonal antibody to PCSK1 on HeLa cell. [antibody concentration 30 ug/ml]
    detail
  • IHC - PCSK1 Antibody (clone 3D2) ALS14054
    Anti-PCSK1 antibody IHC of human brain, cortex.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession P29120
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Clone Names 3D2
Calculated MW 84kDa
Dilution IF (30 µg/ml), IHC-P (10 µg/ml), WB (1:500-1:1000)
Additional Information
Gene ID 5122
Other Names Neuroendocrine convertase 1, NEC 1, 3.4.21.93, Prohormone convertase 1, Proprotein convertase 1, PC1, PCSK1, NEC1
Target/Specificity Human PCSK1
Reconstitution & Storage Store at -20°C
PrecautionsPCSK1 Antibody (clone 3D2) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PCSK1
Synonyms NEC1
Function Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP.
Cellular Location Cytoplasmic vesicle, secretory vesicle. Note=Localized in the secretion granules
Research Areas
Citations (0)
citation

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Background

Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin.

References

Creemers J.W.M.,et al.FEBS Lett. 300:82-88(1992).
Seidah N.G.,et al.DNA Cell Biol. 11:283-289(1992).
Ohagi S.,et al.Diabetes 45:897-901(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Schmutz J.,et al.Nature 431:268-274(2004).

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$ 533.50
Cat# ALS14054
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