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STAT5B Antibody (clone 2D1)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, E |
|---|---|
| Primary Accession | P51692 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 2D1 |
| Calculated MW | 90kDa |
| Dilution | IF (10 µg/ml), IHC-P (5 µg/ml), |
| Gene ID | 6777 |
|---|---|
| Other Names | Signal transducer and activator of transcription 5B, STAT5B |
| Target/Specificity | Human STAT5b |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
| Precautions | STAT5B Antibody (clone 2D1) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | STAT5B |
|---|---|
| Function | Carries out a dual function: signal transduction and activation of transcription (PubMed:29844444). Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription. Positively regulates hematopoietic/erythroid differentiation. |
| Cellular Location | Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription.
References
Silva C.M.,et al.Mol. Endocrinol. 10:508-518(1996).
Silva C.M.,et al.Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
Lin J.-X.,et al.J. Biol. Chem. 271:10738-10744(1996).
Ambrosio R.,et al.Gene 285:311-318(2002).
Sawka-Verhelle D.,et al.Eur. J. Biochem. 250:411-417(1997).
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