ALDOA / Aldolase A Antibody
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
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Primary Accession | P04075 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Calculated MW | 39kDa |
Dilution | IHC-P (20 µg/ml), WB (1:1000), |
Gene ID | 226 |
---|---|
Other Names | Fructose-bisphosphate aldolase A, 4.1.2.13, Lung cancer antigen NY-LU-1, Muscle-type aldolase, ALDOA, ALDA |
Target/Specificity | Anti-Aldolase A recognizes Aldolase A expression in Hela whole cell lysate. |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
Precautions | ALDOA / Aldolase A Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ALDOA (HGNC:414) |
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Synonyms | ALDA |
Function | Catalyzes the reversible conversion of beta-D-fructose 1,6- bisphosphate (FBP) into two triose phosphate and plays a key role in glycolysis and gluconeogenesis (PubMed:14766013). In addition, may also function as scaffolding protein (By similarity). |
Cellular Location | Cytoplasm, myofibril, sarcomere, I band {ECO:0000250|UniProtKB:P00883}. Cytoplasm, myofibril, sarcomere, M line {ECO:0000250|UniProtKB:P00883}. Note=In skeletal muscle, accumulates around the M line and within the I band, colocalizing with FBP2 on both sides of the Z line in the absence of Ca(2+) {ECO:0000250|UniProtKB:P00883} |
Volume | 50 µl |
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Background
Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity).
References
Sakakibara M.,et al.Biochem. Biophys. Res. Commun. 131:413-420(1985).
Izzo P.,et al.Eur. J. Biochem. 164:9-13(1987).
Izzo P.,et al.Eur. J. Biochem. 174:569-578(1988).
Mukai T.,et al.Eur. J. Biochem. 195:781-787(1991).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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