CLTA / CLTB Antibody (Internal)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, IHC-P, E |
|---|---|
| Primary Accession | P09496 |
| Other Accession | P09497 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Hamster, Monkey, Pig, Chicken, Horse, Xenopus, Bovine, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 27077 Da |
| Dilution | ELISA (1:32000), IHC-P (2.5-3.75 µg/ml), WB (0.1-0.3 µg/ml) |
| Gene ID | 1211 |
|---|---|
| Other Names | Clathrin light chain A, Lca, CLTA |
| Target/Specificity | Human CLTA. This antibody is expected to recognize all reported isoforms of light chains a and b. |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | CLTA / CLTB Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CLTA |
|---|---|
| Function | Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Acts as a component of the TACC3/ch- TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter- microtubule bridge (PubMed:15858577, PubMed:21297582). |
| Cellular Location | Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, spindle Note=Cytoplasmic face of coated pits and vesicles. In complex with TACC3 and CKAP5 (forming the TACC3/ch-TOG/clathrin complex) localized to inter-microtubule bridges in mitotic spindles. |

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