FE65L1 / APBB2 Antibody (aa471-520)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q92870 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 83kDa |
Dilution | ELISA (1:40000), IHC-P (10 µg/ml), WB (1:500-1:1000) |
Gene ID | 323 |
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Other Names | Amyloid beta A4 precursor protein-binding family B member 2, Protein Fe65-like 1, APBB2, FE65L, FE65L1 |
Target/Specificity | APBB2 Antibody detects endogenous levels of total APBB2 protein. |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
Precautions | FE65L1 / APBB2 Antibody (aa471-520) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | APBB2 (HGNC:582) |
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Function | Plays a role in the maintenance of lens transparency, and may also play a role in muscle cell strength (By similarity). Involved in hippocampal neurite branching and neuromuscular junction formation, as a result plays a role in spatial memory functioning (By similarity). Activates transcription of APP (PubMed:14527950). |
Cellular Location | Endoplasmic reticulum. Golgi apparatus. Early endosome |
Tissue Location | Widely expressed.. |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
May modulate the internalization of beta-amyloid precursor protein.
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Totoki Y.,et al.Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).
Guenette S.Y.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:10832-10837(1996).
Gauci S.,et al.Anal. Chem. 81:4493-4501(2009).
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